Monday, August 24, 2020

Legal system and method Essay Example | Topics and Well Written Essays - 1000 words

Legitimate framework and strategy - Essay Example Four Judges heard the case as there were two interests heard together. They were heard together as the two of them included translation of segment 3 of the Homicide Act 1957. 3. Which judge led the seat and passed on the judgment? Compose a short true to life note on this adjudicator, including his later profession. What dubious articulation did he make about Sharia law, in 2008? Name and date three out-of court-talks made by this appointed authority. How might you sum up his perspectives on human rights? Ruler Phillips CJ led and conveyed the judgment. Nicholas Addison Phillips was conceived in 1938 and had his training at Bryanston School, Blandofrd, Dorset and Kings College, Cambridge. He served in Royal Navy. He was enlisted into the bar in 1962 and began his legal assistance as a Recorder in 1982. After his stretch as a High Court judge in 1987 and an intrigue court judge in 1995, he turned into a Lord of bids in 1999 and Master of the Rolls at the Court of Appeal, Civil divisio n in June 2000. During his residency, he heard interests of General Augusto Pincohet, previous tyrant of Chile and decided that he was not qualified for insusceptibility from removal. He managed notable preliminaries including the interests from Maxwell siblings and Barlow Clowes, a venture organization. He likewise led the BSE enquiry and inferred that an opportune activity by the legislature would have forestalled the spread of the infection. Known for his effortlessness of cycling to court, he is hitched to Cristylle Marie-Therese Rouffiac and has two children.1,2. During his discourse before the London Muslim Council on 3 July 2008, he communicated that he was agreeable to Sharia law being presented in England and Wales furnished it didn't strife with the laws of the nation or didn't bring about serious disciplines being forced. Including that there had been across the board confusion about Sharia law in England, he supported that it could be utilized for elective contest goals structures, for example, intercession and mediation other than use of the Sharia law to marriage customs. He additionally invited presentation of Islamic money related items. 3. Master Phillip’s three out of court discourses: 1) â€Å"The Supreme Court And Other Constitutional Changes In The UK† before â€Å"Members Of The Royal Court The Jersey Law Society and Members Of The States Of Jersey â€Å" at The Royal Court St Helier Jersey second May 2008. 2) â€Å"Lord Mayor’s Dinner for the Judges† at the Mansion House on 15 July 2008. 3) â€Å"Equality under the steady gaze of the Law† at East London Muslim Center on 3 July 2008. Ruler Phillip has said that Human Rights are not hampering the endeavors of the administration to battle against fear based oppression. He reminds that Britain has invited exiles from everywhere throughout the world after the World War II to promise them assurance from infringement of their human rights. â€Å"The purport ed 'war against psychological oppression' isn't so much a military as an ideological fight. Regard for human rights is a key weapon in that ideological battle.†4 4. Who was the subsequent positioning appointed authority for the situation? What was his job at that point? What is his activity now? Compose a concise true to life note on him. What is his uncommon relationship with Kingston University? Name and date three out-of-court talks made by this appointed authority. What is his notoriety on condemning? Second positioning adjudicator was Justice Poole. Sir David Anthony Poole was conceived on 8 June 1938 and passed on 18 June 2006 in a matter of seconds

Saturday, August 22, 2020

Methods of Data Collection Assignment Example | Topics and Well Written Essays - 750 words

Techniques for Data Collection - Assignment Example In an organized meeting, there are set of inquiries that are posed by the specialist and there is simply this. (Leedy,1997). Face - to - face talk with information assortment strategy has an unmistakable preferred position that empowers the scientist to think of a report that has potential members. Subsequently this makes him ready to pick up their participation. In overview inquire about, this meeting produces the most noteworthy reaction rates. It additionally empowers the analyst to have the option to explain answers that are vague, look for follow-up data and when fitting. A portion of the impediments incorporate tedious, costly and unrealistic when huge examples are utilized. (Leedy,1997). Phone interviews technique for information assortment are more affordable and less tedious and the specialist has simple access to anybody on the planet with a phone. The restrictions are that the pace of reaction isn't that high as that of the up close and personal meeting yet moderately higher when contrasted with the sent poll. There might be predispositions in the example whereby the people without any telephones are remembered for the populace where the scientist needs to draw surmisings from. PC Assisted Personal Interviewing includes individual meeting, whereby the questioner joins a hand-held PC or a PC to enter the data legitimately into the database as opposed to finishing a survey. This information assortment strategy spares time during information preparing. It likewise spares the questioner from having many polls. In any case, then again, this strategy for information assortment can be costly to set up and needs the questioners to have a PC just as composing aptitudes (Markham, 2004). Polls ordinarily utilize rating scales and Checklist. These gadgets normally help in evaluating and rearranging people groups mentalities and practices. An agenda is a rundown of qualities, practices or different elements which the analyst is intrigued in.â â

Friday, July 17, 2020

Getting Help for Social Anxiety Disorder at College

Getting Help for Social Anxiety Disorder at College Social Anxiety Disorder Work and School Print Getting Help for Social Anxiety Disorder at College By Arlin Cuncic Arlin Cuncic, MA, is the author of Therapy in Focus: What to Expect from CBT for Social Anxiety Disorder and 7 Weeks to Reduce Anxiety. Learn about our editorial policy Arlin Cuncic Updated on July 16, 2019 Social Anxiety Disorder Overview Symptoms & Diagnosis Causes Treatment Living With In Children Getty / Hero Images If you are struggling with  social anxiety disorder (SAD)  at college, it can be difficult to manage the everyday aspects of being a student, such as making new friends and attending classes. You Are Not Alone According to a 2011 national survey, more than 62 percent of students with mental health problems who withdrew from college did so because of those issues. Anxiety disorders are among the most prevalent mental health problems experienced by college students today. Understanding Social Anxiety Disorder If you have lived with anxiety for a long time, it may be hard to understand that your symptoms are a diagnosable illness that can be treated. If you have not already been diagnosed, a good place to start is to read about the symptoms of SAD and criteria for diagnosis. How Having SAD May Affect You in College From approaching professors to making new friends and initiating romantic relationships, much of campus life is social. If your SAD is left untreated, all aspects of your college experience may be affected.Academics:  You may find it hard to participate in class, ask questions, get help with homework, join study groups, give presentations, and approach professors.Social activities:  You may be less likely to participate in clubs and sports, to initiate friendships or romantic relationships, and to stand up for yourself in difficult situations.Alcohol abuse:  Students with severe social anxiety are at increased risk of problem drinking if alcohol is used as a coping strategy. How to Get Help SAD is a  highly treatable  disorder with medication and/or therapy. Receiving a proper diagnosis and treatment is important in managing this illness. The first line of treatment is usually  medication  and/or  cognitive-behavioral therapy (CBT). As a student, you may have access to an on-campus mental health center. Often, these will be staffed with therapists, psychologists, or student interns, and will offer a variety of services such as individual and group therapy. Therapy is usually short-term and may be free or available for a fee. If your college or university does not have a mental health center, look for a medical center either on campus or in the community and ask for a referral to a mental health professional. Another alternative is to investigate whether the psychology or psychiatry department at your school offers counseling or medication as part of ongoing research studies. Often, these types of studies are posted on the departments websites. Participation is generally anonymous and they will assess your symptoms to ensure that the treatment is appropriate for your situation. The 9 Best Online Therapy Programs Coping With SAD at College As a college or university student, you can do additional things on your own while receiving treatment. Think about using these strategies as you progress through treatment and begin to feel more comfortable in social situations. Building Friendships Smile, nod, or say hello to classmates.Make comments about assignments or exams to a nearby classmate. Repeat this process at each class, gradually including more classmates until it seems more natural to talk with them.As you feel more comfortable, bring up the idea of a study group or getting together for recreation.If getting to know others in class is difficult, consider joining a service organization on campus. Working together with others toward a common goal is a great way to get to know people.Consider approaching others who seem shy or nervousâ€"they may be less intimidating. How to Make Friends When You Have SAD Body Language and Speech Maintain frequent eye contact with others.Have a relaxed but alert posture.Practice speaking in a moderately loud voice. Conversation Topics Give compliments.Read up on current events and campus news.Be a curious listener, ask open-ended questions starting with why, how, what, or when. Class Presentations Most people get butterflies before speaking in front of a group. However, the initial nervousness usually subsides as they begin speaking and become involved in their topic and with the audience. The opposite tends to happen to people who have SAD. They remain nervous during their speech and became focused on their own anxiety symptoms such as a quivering voice, dry mouth, blushing, rapid heartbeat, and feelings of dread and panic. You will probably at some point be required to give a presentation. If you suffer from severe performance anxiety,  behavioral therapy  such as  systemic desensitization  can be helpful. You can also do several things on your own to help lessen the impact of your anxiety: If possible, choose a topic that you are really passionate about so that you will get enjoyment from sharing your knowledge.Try to get the audience involved at the beginning of your presentation to take some pressure off of yourself. Consider asking your audiences opinion on a topic, having them break into small groups to discuss an issue, or asking for a volunteer to help you demonstrate some aspect of your presentation. Top Tips for Managing Public Speaking Anxiety Positive Lifestyle Coping Strategies Some positive coping strategies that you can start using today include: Exercise Regular exercise is good for maintaining both a healthy mind and body. Choose an activity that you will stick with and enjoy. Go for a walk or jog, try out that new yoga video or just play some frisbee! Your college or university may even offer on-campus facilities or exercise classesâ€"with the added bonus of the chance to make some new friends. Proper Nutrition The typical student diet can wreak havoc on your health. Try to eat regular meals and snacks throughout the day, and avoid caffeine and sugar when possible as these may aggravate anxiety. Using a Healthy Diet and Exercise for Reducing Anxiety A Word From Verywell As a student with social anxiety disorder,  you will face more challenges at college or university. However, with proper diagnosis, treatment, and coping strategies, your odds of having a fulfilling experience are very high. Remember to take every day as it comes, be mindful of your anxious thoughts, and focus on your goals both in terms of your education, making friends, and growing as an individual.

Thursday, May 21, 2020

Huck Finns Ending Essay - 1282 Words

Dear Mark Twain, nbsp;nbsp;nbsp;nbsp;nbsp;After reading your famous novel, â€Å"The Adventures of Huckleberry Finn,† I don’t feel that the ending you have created is suitable for the book. Throughout the entire novel, Huck is going to all extremes to help out a friend in need, Jim. As a slave, Jim is grateful for having such an honest and open friend like Huck, but it seems as if when he finds out he was free all along, things change. When Jim and Huck found themselves at the end of their journey, neither had anything left to run from because Huck’s dad was dead and Jim found out that Mrs. Watson freed him when she passed away a few months ago and hoped he would soon be with his family. Because of this ending of your choice, we never†¦show more content†¦I do feel that it is too long-winded and a downfall to such a great novel, but it is very important in reinforcing the message put forth in the rest of the novel; the greatest of which is the shortcomings of modern soci ety and the hypocrisy and arrogance, and even the stupidity of people of Twain’s time. nbsp;nbsp;nbsp;nbsp;nbsp;Aside from the ending as a downfall, The Adventures of Huckleberry Finn taught an important lesson, one that showed the importance of the self in the maturing process. We saw Huck grow up by having the river as a place of solitude and thought, where he was able to participate in society at times, and also sit back and observe society. Through the childs eye we see how ignorant and mob-like we can all be. Then nature, peace, and logic are presented in the form of the river where Huck goes to think. Though no concise answer is given, the literature forces the reader to examine their surroundings, and question their leaders, which can also lead into this great disappointment. Because we idolize Huck for his individualism and beliefs, the end of the novel lets all the readers down. We can no longer refer to Huck as a hero because he never got Jim to freedom, instead prevented him from it. Although Huck loved Jim, he feared his future and what would happen to him if he were caughtShow MoreRelatedThe Adventures Of Huckleberry Finn And Its Characterization951 Words   |  4 PagesHon. 2nd 3 March 2016 The Adventures of Huckleberry Finn and its Characterization In The Adventures of Huckleberry Finn by Mark Twain, there is a large use of characterization to develop the characters and is influenced by the time period. Mark Twain was born in 1835, and lived to see the Civil War start. This is a big influence on his writing, because his two most famous works, The Adventures of Tom Sawyer and The Adventures of Huckleberry Finn. They both take place in the time before the CivilRead More A Psychoanalytic Reading of Mark Twains The Adventures of Huckleberry Finn1582 Words   |  7 PagesA Psychoanalytic Reading of Huckleberry Finn   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Psychoanalytic conditions, stages and symptoms pervade the seemingly simplistic narration of a child-narrator, Huck Finn. Such Freudian psychoanalytic ideas as Thanatos, repressed desires and how they seek their way back through dream work, through parapraxis, can all find examples in this fiction. Besides, Lacanian concept of the unconscious as the nucleus of our being, as an orderly network, as well as his famous theory the mirrorRead MoreRacism of Yesterday and Today Essay1655 Words   |  7 PagesThe Adventures of Huckleberry Finn was written by Mark Twain in the middle of the nineteenth century. Much of the inspiration for the book came from Mark Twain’s own encounters. Twain’s experiences as a steamboat pilot from 1835 to 1845 provided a great deal of the historical context for his work. The novel revolves around a southern boy, Huck, and a slave named Jim who both reject society by running away in hopes of finding freedom. The Adventure s of Huckleberry Finn highlights and portrays the crueltyRead MoreThe Relationship Between Trilling, And Huckleberry Finn By Leo Marx1315 Words   |  6 PagesFrom Mr. Eliot, Mr. Trilling, and Huckleberry Finn by Leo Marx In this essay, Leo Marx is talking about how the ending of the story in the Adventures of Huckleberry Finn is not well connected to the whole meaning of the events that happens throughout the story. He is saying that the ending of the story throws out completely the plot. Marx is explaining how interesting was the journey that Huck and Jim had, searching for Jim s freedom, but to him everything what they did to get Jim out of thisRead MoreAnalysis Of Mark Twain s The Adventures Of Huckleberry Finn 1701 Words   |  7 Pagesâ€Æ' A work of literature can be read by ten different people, and it will be understood ten different ways; Mark Twain’s The Adventures of Huckleberry Finn is no exception. At the end of the novel, Tom reveals his plans for the â€Å"evasion† which is relatively immoral, but Tom and Huck would never know whether it was or was not. In addition to its blind cruelty, it is misleading in that it seems as if it is meant to be interpreted, which is one reason why it is constantly critiqued. Another reason itRead MoreThe Adventures Of Huckleberry Finn By Mark Twain1648 Words   |  7 Pagesrealism movement. Mark Twain was a skeptic about religion, and had especially harsh criticism of extreme evangelical Christians. Adventures of Huckleberry Finn is one of the most prominent representations of Mark Twain s Realism. Adventures of Huckleberry Finn is about a neglected 13-year old, whose father is a drunk. We see the world from Huck s point of view as he attempts to decipher the wo rld around him. Along the way, Mark Twain exploits social problems in this world and depicts the hypocrisyRead MoreComparison of Jim from Huckleberry Finn or Ethan Frome1540 Words   |  6 Pages How can you compare Jims situation from Huck FInn to Ethan Fromes situation. How are the two characters alike and how are they different. Base your answers on information regarding their genre. Which character has more of a chance of making it and why? Jim from The Adventure of Huckleberry Finn and Ethan Frome from Ethan Frome share many incidents in a indistinguishable occurrence. They also share many qualities that allow each of these two characters to have divergent and duplicate qualitiesRead MoreThe Adventures Of Huckleberry Finn By Mark Twain1164 Words   |  5 PagesResearch Paper In The Adventures of Huckleberry Finn, Mark Twain writes about the events in Huckleberry Finn’s life and the people around him. Huckleberry Finn tells the tale of life in the nineteenth century through the eyes of a 14-year-old boy struggling to find his place in this society. Throughout the story Huck deals with several moral issues; such as slavery, his distrust of society, and social order. In this essay I will discuss moral issues that Huck Finn faces in the story. The story takes placesRead MoreThe Adventures Of Huckleberry Finn By Mark Twain1574 Words   |  7 PagesAdventures of Huckleberry Finn, verbalized that â€Å"the relative strengths of good and evil in the world are drastically unbalanced and society is far from being the idyllic, equal post-Civil War affair it pretends to be.† Twain has an authentic, albeit marginally controversial means by which he tells the story of a white thirteen year old, southern, and relatively illiterate boy named Huckleberry Finn. While inquiring whether or not Adventures of Huckleberry Finn, has a flawed ending due to the lack of moralRead More Struggle for Freedom in Adventures of Huckleberry Finn Essay1136 Words   |  5 PagesStruggle for Freedom in Adventures of Huckleberry Finn   Ã‚  Ã‚  Ã‚  Ã‚   The Widow Douglas, she took me for her son, and allowed she would sivilize me; but it was rough living in the house all the time, considering how dismal regular and decent the widow was in all her ways; and so when I couldnt stand it no longer, I lit out. The aforementioned quotation best describes Hucks philosophy when faced with ties that bind. When he is unable to take the restrictions of life any longer, whether

Wednesday, May 6, 2020

A Short Story - 1553 Words

â€Å"Hawke. Youre awake?† Isabela asked. Reposing at her side she passed the right index around the nipple-areola of her and, smiling on hearing a small giggle. â€Å"Yes, my dear sweet Rivaini?† Positioning the head on the Isabela neck and kissing her nape with eyes closed, making the Rivaini quiver. â€Å"The last trick you did. It was amazing.† Moving up while caressing the upper chest and following towards the neck until her right cheek, pressing the thumb on her lips. â€Å"And youre always trying new things for me..., Spells to increase pleasure and your cock and pussy are wonderful, also many positions you mastered.† â€Å"Hmm... Bela?† Hawke with eyes now open and unsure of what direction that talk is going to. â€Å"Something wrong? Did something†¦show more content†¦Ã¢â‚¬Å"You... Ah! Fuck,† Isabela broke the kiss and looked at Hawkes eyes, â€Å"This is one of the reasons I cant abandon you, Hawke. I want you to be mine and mine only.† â€Å"What?† A sudden stop while staying with hands extended on the bed looking at her, â€Å"Bela.† â€Å"I thought about it a lot.† Isabela said to her and started to thought, She loves me, and I love her; Furthermore, she fucking commanded four ships to kill one of the most dangerous known men for me. Before that also dueled one of the most fearsome Qunari this world took notice gaining my heart. Being not enough, she gave me a fucking ship for love alone.† â€Å"Hawke. No, Marian, I love you, and I want you to be mine and, no one else forever, what you always did for me. I want to repay, so would you accept my feelings?† Her wet amber eyes looking at Hawkes blue eyes crying and between hiccups, Bela. I always loved you. The city still burning while the rest of the Qunari army goes downstairs carrying the Tome of Koslum quietly. Being followed by the Templars led by Meredith and with Orsino at her side to ensure that they will leave Kirkwall. On the top of the stairs where a recent duel happened. Hawke looked down to the Arishok beheaded by her staff, on a challenge she received to protect someone she cares and love. â€Å"You bitch born whore. You will not leave. Not now,† Aveline shouted loud enough to make Hawke snap from her thoughts. â€Å"You have a lot to answer for..., And you will abandon her, after what justShow MoreRelatedshort story1018 Words   |  5 Pagesï » ¿Short Stories:  Ã‚  Characteristics †¢Short  - Can usually be read in one sitting. †¢Concise:  Ã‚  Information offered in the story is relevant to the tale being told.  Ã‚  This is unlike a novel, where the story can diverge from the main plot †¢Usually tries to leave behind a  single impression  or effect.  Ã‚  Usually, though not always built around one character, place, idea, or act. †¢Because they are concise, writers depend on the reader bringing  personal experiences  and  prior knowledge  to the story. Four MajorRead MoreThe Short Stories Ideas For Writing A Short Story Essay1097 Words   |  5 Pageswriting a short story. Many a time, writers run out of these short story ideas upon exhausting their sources of short story ideas. If you are one of these writers, who have run out of short story ideas, and the deadline you have for coming up with a short story is running out, the short story writing prompts below will surely help you. Additionally, if you are being tormented by the blank Microsoft Word document staring at you because you are not able to come up with the best short story idea, youRead MoreShort Story1804 Words   |  8 PagesShort story: Definition and History. A  short story  like any other term does not have only one definition, it has many definitions, but all of them are similar in a general idea. According to The World Book Encyclopedia (1994, Vol. 12, L-354), â€Å"the short story is a short work of fiction that usually centers around a single incident. Because of its shorter length, the characters and situations are fewer and less complicated than those of a novel.† In the Cambridge Advanced Learner’s DictionaryRead MoreShort Stories648 Words   |  3 Pageswhat the title to the short story is. The short story theme I am going conduct on is â€Å"The Secret Life of Walter Mitty’ by James Thurber (1973). In this short story the literary elements being used is plot and symbols and the theme being full of distractions and disruption. The narrator is giving a third person point of view in sharing the thoughts of the characters. Walter Mitty the daydreamer is very humorous in the different plots of his dr ifting off. In the start of the story the plot, symbols,Read MoreShort Stories1125 Words   |  5 PagesThe themes of short stories are often relevant to real life? To what extent do you agree with this view? In the short stories â€Å"Miss Brill† and â€Å"Frau Brechenmacher attends a wedding† written by Katherine Mansfield, the themes which are relevant to real life in Miss Brill are isolation and appearance versus reality. Likewise Frau Brechenmacher suffers through isolation throughout the story and also male dominance is one of the major themes that are highlighted in the story. These themes areRead MoreShort Story and People1473 Words   |  6 Pagesï » ¿Title: Story Of An Hour Author: Kate Chopin I. On The Elements / Literary Concepts The short story Story Of An Hour is all about the series of emotions that the protagonist, Mrs. Mallard showed to the readers. With the kind of plot of this short story, it actually refers to the moments that Mrs. Mallard knew that all this time, her husband was alive. For the symbol, I like the title of this short story because it actually symbolizes the time where Mrs. Mallard died with joy. And with thatRead MoreShort Story Essay1294 Words   |  6 PagesA short story concentrates on creating a single dynamic effect and is limited in character and situation. It is a language of maximum yet economical effect. Every word must do a job, sometimes several jobs. Short stories are filled with numerous language and sound devices. These language and sound devices create a stronger image of the scenario or the characters within the text, which contribute to the overall pre-designed effect.As it is shown in the metaphor lipstick bleeding gently in CinnamonRead MoreGothic Short Story1447 W ords   |  6 Pages The End. In the short story, â€Å"Emma Barrett,† the reader follows a search party group searching for a missing girl named Emma deep in a forest in Oregon. The story follows through first person narration by a group member named Holden. This story would be considered a gothic short story because of its use of setting, theme, symbolism, and literary devices used to portray the horror of a missing six-year-old girl. Plot is the literal chronological development of the story, the sequence of eventsRead MoreRacism in the Short Stories1837 Words   |  7 PagesOften we read stories that tell stories of mixing the grouping may not always be what is legal or what people consider moral at the time. The things that you can learn from someone who is not like you is amazing if people took the time to consider this before judging someone the world as we know it would be a completely different place. The notion to overlook someone because they are not the same race, gender, creed, religion seems to be the way of the world for a long time. Racism is so prevalentRead MoreThe Idol Short Story1728 Words   |  7 PagesThe short stories â€Å"The Idol† by Adolfo Bioy Casares and â€Å"Axolotl† by Julio Cortà ¡zar address the notion of obsession, and the resulting harm that can come from it. Like all addictions, obsession makes one feel overwhelmed, as a single thought comes to continuously intr uding our mind, causing the individual to not be able to ignore these thoughts. In â€Å"Axolotl†, the narrator is drawn upon the axolotls at the Jardin des Plantes aquarium and his fascination towards the axolotls becomes an obsession. In

Part Two Chapter IV Free Essays

string(66) " to her in tight T-shirts; they looked barely out of their teens\." IV Samantha’s dinner invitation to Kay had been motivated by a mixture of vengefulness and boredom. She saw it as retaliation against Miles, who was always busy with schemes in which he gave her no say but with which he expected her to co-operate; she wanted to see how he liked it when she arranged things without consulting him. Then she would be stealing a march on Maureen and Shirley, those nosy old crones, who were so fascinated by Gavin’s private affairs but knew next to nothing about the relationship between him and his London girlfriend. We will write a custom essay sample on Part Two Chapter IV or any similar topic only for you Order Now Finally, it would afford her another opportunity to sharpen her claws on Gavin for being pusillanimous and indecisive about his love life: she might talk about weddings in front of Kay or say how nice it was to see Gavin making a commitment at last. However, her plans for the discomfiture of others gave Samantha less pleasure than she had hoped. When on Saturday morning she told Miles what she had done, he reacted with suspicious enthusiasm. ‘Great, yeah, we haven’t had Gavin round for ages. And nice for you to get to know Kay.’ ‘Why?’ ‘Well, you always got on with Lisa, didn’t you?’ ‘Miles, I hated Lisa.’ ‘Well, OK †¦ maybe you’ll like Kay better!’ She glared at him, wondering where all this good humour was coming from. Lexie and Libby, home for the weekend and cooped up in the house because of the rain, were watching a music DVD in the sitting room; a guitar-laden ballad blared through to the kitchen where their parents stood talking. ‘Listen,’ said Miles, brandishing his mobile, ‘Aubrey wants to have a talk with me about the council. I’ve just called Dad, and the Fawleys have invited us all to dinner tonight at Sweetlove – ‘ ‘No thanks,’ said Samantha, cutting him off. She was suddenly full of a fury she could barely explain, even to herself. She walked out of the room. They argued in low voices all over the house through the day, trying not to spoil their daughters’ weekend. Samantha refused to change her mind or to discuss her reasons. Miles, afraid of getting angry at her, was alternately conciliatory and cold. ‘How do you think it’s going to look if you don’t come?’ he said at ten to eight that evening, standing in the doorway of the sitting room, ready to leave, wearing a suit and tie. ‘It’s nothing to do with me, Miles,’ Samantha said. ‘You’re the one running for office.’ She liked watching him dither. She knew that he was terrified of being late, yet wondering whether he could still persuade her to go with him. ‘You know they’ll be expecting both of us.’ ‘Really? Nobody sent me an invitation.’ ‘Oh, come off it, Sam, you know they meant – they took it for granted – ‘ ‘More fool them, then. I’ve told you, I don’t fancy it. You’d better hurry. You don’t want to keep Mummy and Daddy waiting.’ He left. She listened to the car reversing out of the drive, then went into the kitchen, opened a bottle of wine and brought it back into the sitting room with a glass. She kept picturing Howard, Shirley and Miles all having dinner together at Sweetlove House. It would surely be the first orgasm Shirley had had in years. Her thoughts swerved irresistibly to what her accountant had said to her during the week. Profits were way down, whatever she had pretended to Howard. The accountant had actually suggested closing the shop and concentrating on the online side of the business. This would be an admission of failure that Samantha was not prepared to make. For one thing, Shirley would love it if the shop closed; she had been a bitch about it from the start. I’m sorry, Sam, it’s not really my taste †¦ just a teeny bit over the top †¦ But Samantha loved her little red and black shop in Yarvil; loved getting away from Pagford every day, chatting to customers, gossiping with Carly, her assistant. Her world would be tiny without the shop she had nurtured for fourteen years; it would contract, in short, to Pagford. (Pagford, bloody Pagford. Samantha had never meant to live here. She and Miles had planned a year out before starting work, a round-the-world trip. They had their itinerary mapped out, their visas ready. Samantha had dreamed about walking barefoot and hand in hand on long white Australian beaches. And then she had found out that she was pregnant. She had come down to visit him at ‘Ambleside’, a day after she had taken the pregnancy test, one week after their graduation. They were supposed to be leaving for Singapore in eight days’ time. Samantha had not wanted to tell Miles in his parents’ house; she was afraid that they would overhear. Shirley seemed to be behind every door Samantha opened in the bungalow. So she waited until they were sitting at a dark corner table in the Black Canon. She remembered the rigid line of Miles’ jaw when she told him; he seemed, in some indefinable way, to become older as the news hit him. He did not speak for several petrified seconds. Then he said, ‘Right. We’ll get married.’ He told her that he had already bought her a ring, that he had been planning to propose somewhere good, somewhere like the top of Ayers Rock. Sure enough, when they got back to the bungalow, he unearthed the little box from where he had already hidden it in his rucksack. It was a small solitaire diamond from a jeweller’s in Yarvil; he had bought it with some of the money his grandmother had left him. Samantha had sat on the edge of Miles’ bed and cried and cried. They had married three months later.) Alone with her bottle of wine, Samantha turned on the television. It brought up the DVD Lexie and Libby had been watching: a frozen image of four young men singing to her in tight T-shirts; they looked barely out of their teens. You read "Part Two Chapter IV" in category "Essay examples" She pressed play. After the boys finished their song, the DVD cut to an interview. Samantha slugged back her wine, watching the band joking with each other, then becoming earnest as they discussed how much they loved their fans. She thought that she would have known them as Americans even if the sound had been off. Their teeth were perfect. It grew late; she paused the DVD, went upstairs and told the girls to leave the PlayStation and go to bed; then she returned to the sitting room, where she was three-quarters of the way down the bottle of wine. She had not turned on the lamps. She pressed play and kept drinking. When the DVD finished, she put it back to the beginning and watched the bit she had missed. One of the boys appeared significantly more mature than the other three. He was broader across the shoulders; biceps bulged beneath the short sleeves of his T-shirt; he had a thick strong neck and a square jaw. Samantha watched him undulating, staring into the camera with a detached serious expression on his handsome face, which was all planes and angles and winged black eyebrows. She thought of sex with Miles. It had last happened three weeks previously. His performance was as predictable as a Masonic handshake. One of his favourite sayings was ‘if it’s not broke, don’t fix it’. Samantha emptied the last of the bottle into her glass and imagined making love to the boy on the screen. Her breasts looked better in a bra these days; they spilled everywhere when she lay down; it made her feel flabby and awful. She pictured herself, forced back against a wall, one leg propped up, a dress pushed up to her waist and that strong dark boy with his jeans round his knees, thrusting in and out of her †¦ With a lurch in the pit of her stomach that was almost like happiness, she heard the car turning back into the drive and the beams of the headlights swung around the dark sitting room. She fumbled with the controls to turn over to the news, which took her much longer than it ought to have done; she shoved the empty wine bottle under the sofa and clutched her almost empty glass as a prop. The front door opened and closed. Miles entered the room behind her. ‘Why are you sitting here in the dark?’ He turned on a lamp and she glanced up at him. He was as well groomed as he had been when he left, except for the raindrops on the shoulders of his jacket. ‘How was dinner?’ ‘Fine,’ he said. ‘You were missed. Aubrey and Julia were sorry you couldn’t make it.’ ‘Oh, I’m sure. And I’ll bet your mother cried with disappointment.’ He sat down in an armchair at right angles to her, staring at her. She pushed her hair out of her eyes. ‘What’s this all about, Sam?’ ‘If you don’t know, Miles – ‘ But she was not sure herself; or at least, she did not know how to condense this sprawling sense of ill-usage into a coherent accusation. ‘I can’t see how me standing for the Parish Council – ‘ ‘Oh, for God’s sake, Miles!’ she shouted, and was then slightly taken aback by how loud her voice was. ‘Explain to me, please,’ he said, ‘what possible difference it can make to you?’ She glared at him, struggling to articulate it for his pedantic legal mind, which was like a fiddling pair of tweezers in the way that it seized on poor choices of word, yet so often failed to grasp the bigger picture. What could she say that he would understand? That she found Howard and Shirley’s endless talk about the council boring as hell? That he was quite tedious enough already, with his endlessly retold anecdotes about the good old days back at the rugby club and his self-congratulatory stories about work, without adding pontifications about the Fields? ‘Well, I was under the impression,’ said Samantha, in their dimly lit sitting room, ‘that we had other plans.’ ‘Like what?’ said Miles. ‘What are you talking about?’ ‘We said,’ Samantha articulated carefully over the rim of her trembling glass, ‘that once the girls were out of school, we’d go travelling. We promised each other that, remember?’ The formless rage and misery that had consumed her since Miles announced his intention to stand for the council had not once led her to mourn the year’s travelling she had missed, but at this moment it seemed to her that that was the real problem; or at least, that it came closest to expressing both the antagonism and the yearning inside her. Miles seemed completely bewildered. ‘What are you talking about?’ ‘When I got pregnant with Lexie,’ Samantha said loudly, ‘and we couldn’t go travelling, and your bloody mother made us get married in double-quick time, and your father got you a job with Edward Collins, you said, we agreed, that we’d do it when the girls were grown up; we said we’d go away and do all the things we missed out on.’ He shook his head slowly. ‘This is news to me,’ he said. ‘Where the hell has this come from?’ ‘Miles, we were in the Black Canon. I told you I was pregnant, and you said – for Christ’s sake, Miles – I told you I was pregnant, and you promised me, you promised – ‘ ‘You want a holiday?’ said Miles. ‘Is that it? You want a holiday?’ ‘No, Miles, I don’t want a bloody holiday, I want – don’t you remember? We said we’d take a year out and do it later, when the kids were grown up!’ ‘Fine, then.’ He seemed unnerved, determined to brush her aside. ‘Fine. When Libby’s eighteen; in four years’ time, we’ll talk about it again. I don’t see how me becoming a councillor affects any of this.’ ‘Well, apart from the bloody boredom of listening to you and your parents whining about the Fields for the rest of our natural lives – ‘ ‘Our natural lives?’ he smirked. ‘As opposed to – ?’ ‘Piss off,’ she spat. ‘Don’t be such a bloody smartarse, Miles, it might impress your mother – ‘ ‘Well, frankly, I still don’t see what the problem – ‘ ‘The problem,’ she shouted, ‘is that this is about our future, Miles. Our future. And I don’t want to bloody talk about it in four years’ time, I want to talk about it now!’ ‘I think you’d better eat something,’ said Miles. He got to his feet. ‘You’ve had enough to drink.’ ‘Screw you, Miles!’ ‘Sorry, if you’re going to be abusive †¦Ã¢â‚¬â„¢ He turned and walked out of the room. She barely stopped herself throwing her wine glass after him. The council: if he got on it, he would never get off; he would never renounce his seat, the chance to be a proper Pagford big shot, like Howard. He was committing himself anew to Pagford, retaking his vows to the town of his birth, to a future quite different from the one he had promised his distraught new fiancee as she sat sobbing on his bed. When had they last talked about travelling the world? She was not sure. Years and years ago, perhaps, but tonight Samantha decided that she, at least, had never changed her mind. Yes, she had always expected that some day they would pack up and leave, in search of heat and freedom, half the globe away from Pagford, Shirley, Mollison and Lowe, the rain, the pettiness and the sameness. Perhaps she had not thought of the white sands of Australia and Singapore with longing for many years, but she would rather be there, even with her heavy thighs and her stretch marks, than here, trapped in Pagford, forced to watch as Miles turned slowly into Howard. She slumped back down on the sofa, groped for the controls, and switched back to Libby’s DVD. The band, now in black and white, was walking slowly along a long empty beach, singing. The broad-shouldered boy’s shirt was flapping open in the breeze. A fine trail of hair led from his navel down into his jeans. How to cite Part Two Chapter IV, Essay examples

Saturday, April 25, 2020

Tregs in Allergies and Autoimmune Diseases

Abstract Tregs refer to subpopulations of T cells that play a role in suppressing the autoimmunity of diseases. They maintain self-tolerance and homeostasis of body’s immunity. Tregs inhibit the proliferation of T cells; hence, they play a role in the prevention of the autoimmunity.Advertising We will write a custom essay sample on Tregs in Allergies and Autoimmune Diseases specifically for you for only $16.05 $11/page Learn More In a lipopolysaccharide challenge carried out using mice models, Tregs were found to control CD4+T cells from causing hypersensitivity, which pointed to their indispensable role in the control of autoimmunity diseases. The investigation of the role of Tregs in allergies entailed in vitro experiments in which models of mouse CD4+CD25+ T cells were used. The cells were found to suppress differentiation of Th2 from CD4+ cells, which inhibited IgE. The IgE acts against antigens that cause allergies. Introduction Tregs (regula tory T cells) prevent autoimmune diseases and infections that arise from organ pathogens. The roles of Tregs in autoimmune diseases and allergies have resulted in a lot of interest. As a result, there have been many studies by clinical researchers to ascertain the functions of Tregs in the allergies and autoimmune diseases. For example, Okeke, Okwor and Uzonna (656) conducted a study to investigate the functions of Tregs. The study entailed a lipopolysaccharide (LPS) in which Tregs were found to prevent unregulated immune activation. In relation to the allergies, the studies investigated the effects of subsets of Tregs in influencing IgE population. The following paper investigates Tregs and their roles in the prevention of allergies and autoimmune diseases. Goals of the Study Prevention of autoimmune diseases is one of the key areas of interest in studies related to Tregs. Schmidt, Oberle and Krammer (4) noted that the function of Tregs in the maintenance of peripheral tolerance ca nnot be underestimated. Therefore, the first goal of this study is to determine the function of Tregs in the immune activation. The second goal is to determine the role of Tregs in the regulation of allergic diseases. Techniques In the study to investigate the role of Tregs in the maintenance of peripheral tolerance, knock out models of murine lymphocyte gene were used. The study included the use of non-lethal dose of LPS. Mice that were SCID or RAG 1 deficient and lacked the T and B cells were investigated for the LPS susceptibility (Okeke, Okwor and Uzonna 656).Advertising Looking for essay on health medicine? Let's see if we can help you! Get your first paper with 15% OFF Learn More In the investigation of the role of Tregs in reducing allergic sensitization, studies that included in vitro differentiation of Th2 from CD4+T cells (Robinson, Larchà © Durham 1389). Findings In the investigation of the role of Tregs in the autoimmunity, depletion of the Tregs resulte d in increased sensitivity to LPS. However, the mice that lacked T and B cells were not sensitive to LPS. The depletion of Tregs resulted in increase in CD4 (+) T cells proliferation that responded to the LPS challenge. The CD4 (+) T cells are normally pathologic. The cells exaggerated the activation of the immune system, which negatively affected the survival of LPS (Okeke, Okwor and Uzonna 659). Investigation of functions of Tregs in allergies found that models of mice CD4+CD25+T cells suppressed the differentiation of Th2 from CD4+T cells. The high levels of IgE were reduced by CD4+CD25–T cells. Transgenic mice with monoclonal populations of T cells increased the levels of IgE. In vitro experiments of models of mouse CD4+CD25+T cells suppressed the differentiation of Th2 in vitro from CD4+T cells. The monoclonal populations of T cells increased the levels of IgE. Discussion The subpopulations of T cells prevent infections induced organ pathology. Tregs act by inhibiting th e TCR Induced proliferation. In the LPS challenge, the use of the murine suppressed the T cells proliferation thus Tregs produced TGF–Î ² that controls autoimmunity. According to Okeke, Okwor and Uzonna (661), subsets of Tregs both in mice and in humans play an importance role in the pathogenesis of autoimmune diseases. Tregs control the homeostasis of T cells by suppressing the proliferation of effectors T cells. The result is the increase in self-tolerance. In vivo experiments have showed that the absence of Tregs leads to autoimmune diseases such as gastritis, arthritis, and thyroiditis. IgE is produced in atopic allergic sensitization. The IgE protects the body from environmental antigens. In normal cases, the control of allergies is done by use of allergen injection immunotherapy (Robinson, Larchà © and Durham 1389). The mechanism involves the modulation of Th2 response.Advertising We will write a custom essay sample on Tregs in Allergies and Autoimmune Diseases s pecifically for you for only $16.05 $11/page Learn More According to Palomares (1236), the subsets of Tregs share common features of Foxp3 expression and inhibit the cytokine IL-10 (TGF–Î ²). The inhibition of functional Tregs compromises the body’s response to allergies. The implication is that the Tregs prevent the responses of IgE. Thus, Tregs contribute to the early development of allergies. Conclusion Tregs enhance self-tolerance and maintain homeostasis by suppression of effectors T cells. The inhibition of the proliferation of T cells results in actions that control autoimmunity diseases. On the other hand, the inhibitory properties of Tregs reduce the population of IgE; hence, compromising body’s response to allergies. Therefore, in designing therapies for allergies, the actions of Tregs and their effects on IgE should be considered. Works Cited Okeke, Emeka, Ifeoma Okwor, and Jude Uzonna. â€Å"Regulatory T cells restrain CD4+ T cells from causing unregulated immune activation and hypersensitivity to lipopolysaccharide challenge.† The Journal of Immunology 193.2 (2014): 655- 662. Print. Palomares, Oscar. â€Å"Role of Tregs in immune regulation of allergic diseases.† European Journal of Immunology 40.5 (2010): 1232-1240. Print. Robinson, Douglas, Mark Larchà ©, and Stephen Durham. â€Å"Tregs and allergic disease.† Journal of Clinical Investigation 114.10 (2004): 1389-1391.Print. Schmidt, Angelika, Nina Oberle, and Peter Krammer. â€Å"Molecular mechanisms of Treg- mediated T cell suppression.† Frontiers in Immuneology 3.1 (2012): 2-13. Print. This essay on Tregs in Allergies and Autoimmune Diseases was written and submitted by user Annabella K. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.